What Is Multiple Sclerosis (MS)?
MS
is a chronic disease that damages the nerves in the spinal cord and
brain, as well as the optic nerves. Sclerosis means scarring, and
people with MS develop multiple areas of scar tissue in response to
the nerve damage. Depending on where the damage occurs, symptoms may
include problems with muscle control, balance, vision, or speech.
MS Symptoms: Weakness or Numbness
Nerve damage can cause:
These symptoms may lead to frequent
tripping or difficulty walking.
MS Symptoms: Vision Problems
More
than half of people with MS experience a vision problem called optic
neuritis. This inflammation of the optic nerve may cause blurred
vision, loss of color vision, eye pain, or blindness, usually in one
eye. The problem is usually temporary and tends to improve within a
few weeks. In many cases, vision problems are the first sign of MS.
MS Symptoms: Speech Problems
Although
less common than vision problems, some people with MS develop slurred
speech. This happens when MS damages the nerves that carry speech
signals from the brain. Some people also have trouble swallowing.
Other MS Symptoms
MS
can take a toll on mental sharpness. Some people may find it takes
longer to solve problems. Others may have mild memory loss or trouble
concentrating. Most people with MS also experience some loss of
bladder control, because signals between the brain and bladder are
interrupted. Finally, fatigue is a common problem. You may feel tired
even after a good night's sleep.
Stroke vs. MS
Confusion,
slurred speech, and muscle weakness can be symptoms of MS, but they
can also be signs of a stroke. Anyone who suddenly has trouble
speaking or moving their limbs should be taken to the ER immediately.
Treating a stroke within the first few hours provides the best odds
of a successful recovery.
How MS Attacks
In
people with MS, the body's own immune system attacks the tissue
surrounding the nerve fibers in the brain, spinal cord, and optic
nerves. This covering is made of a fatty substance called myelin. It
insulates the nerves and helps them send electrical signals that
control movement, speech, and other functions. When myelin is
destroyed, scar tissue forms, and nerve messages are not transmitted
properly.
What Causes MS?
The
roots of MS remain mysterious, but doctors see some surprising
trends. It's most common in regions far from the equator, including
Scandinavia and other parts of Northern Europe. These areas get less
sunlight, so some researchers believe that vitamin D (the "sunshine
vitamin") may be involved. Research suggests a possible link
between vitamin D deficiency and autoimmune disorders, but studies
are ongoing. Genetics appear to play a role, as well.
Who Gets MS?
MS
is at least twice as common in women as it is in men. While it can
strike people of any race, Caucasians appear to be most at risk. The
chances of developing the condition are highest between ages 20 and
50.
Diagnosing MS
Tests
are often used, along with a medical history and neurological exam,
to diagnose MS and rule out other causes of symptoms. More than 90%
of people with MS have scar tissue that shows up on an MRI scan. A
spinal tap can check for abnormalities in the fluid that bathes the
brain and spinal cord. Tests to look at electrical activity of nerves
can also help with diagnosis. Lab tests can help rule out other
autoimmune conditions or infections such as HIV or Lyme disease.
How Does MS Progress?
MS is different in every person.
Doctors usually see four forms:
Relapsing-remitting: Symptoms
flare during acute attacks, then improve nearly completely or
"remit." This is the most common form of MS.
Primary-progressive: MS slowly
but steadily worsens.
Secondary-progressive: Begins
as relapsing-remitting type, then becomes progressive.
Progressive-relapsing: The
underlying disease steadily worsens. The patient has acute relapses,
which may or may not remit. This is the least common form of MS.
MS and Weather
Research
suggests that the disease may be more active during the summer
months. Heat and high humidity may also temporarily worsen symptoms.
Very cold temperatures and sudden changes in temperature may
aggravate symptoms, as well.
Treating MS: Medications
While
there is no cure for MS, there are "disease-modifying drugs"
that can reduce the frequency and severity of MS attacks. Use can
result in less damage to the brain and spinal cord over time, slowing
the progression of disability. When an attack does occur, high-dose
corticosteroids can help cut it short. Many drugs are also available
to manage troubling MS symptoms, such as muscle spasms, incontinence,
and pain.
Treating MS: Pain Management
About
half of people with MS develop some form of pain, either as a result
of a short circuit in the nervous system or because of muscle spasms
or strain. Doctors may prescribe antidepressants and anticonvulsant
medications to ease nerve pain. Pain medicines and anti-spasm drugs
may also be used. Muscle pain often responds well to massage and
physical therapy. Be sure to discuss the options with your doctor if
you find yourself in pain.
Treating MS: Physical Therapy
If
MS affects balance, coordination, or muscle strength, you can learn
to compensate. Physical therapy can help strengthen muscles, combat
stiffness, and get around more easily. Occupational therapy can help
retain coordination in your hands for dressing and writing. And if
you're having trouble speaking or swallowing, a speech therapist can
help.
Complementary Therapies for MS
Many
nontraditional therapies for MS have not been well studied. Some
people say acupuncture relieves symptoms such as muscle spasms and
pain, but research to confirm its value isn't conclusive. Others have
reported benefits from injections of bee venom, but a rigorous study,
lasting 24 weeks, showed no improvements in disability, fatigue, or
the number of MS attacks. It's important to inform your doctor about
any supplements, special diets, or other therapies you want to try.
MS and Pregnancy
Doctors
generally agree that it’s safe for women with MS to get pregnant.
Research suggests no increased risk of complications during
pregnancy. In fact, many women have fewer MS symptoms during
pregnancy. High levels of hormones and proteins may suppress the
immune system, reducing the odds of a new attack. It's best to talk
with your doctors before pregnancy, as certain MS drugs should not be
used while pregnant or nursing. In the early months after
delivery, the odds for a relapse can rise.
Staying Mobile With MS
The
vast majority of people with MS are able to continue walking, though
many benefit from some type of assistive device. Orthotic shoe
inserts or leg braces can help increase stability. When one leg is
stronger than the other, a cane can help. People with significant
problems with their legs may need to use a walker. And a wheelchair
or scooter may be best for those who are very unsteady or tire
easily.
Adapting Your Home for MS
Making
a few changes around the home can help you manage daily activities on
your own. Install grab bars inside and outside the shower or tub. Use
a non-slip mat. Add an elevated seat and safety rails to the toilet.
Lower one of your kitchen counters so you can reach it from a sitting
position. And get rid of any throw rugs, which are a tripping hazard.
MS and Exercise
Exercise
can ease stiffness, fatigue, and other symptoms of MS. But overdoing
it could make things worse. It's best to start slowly. Try exercising
for 10 minutes at a time, then gradually working your way up to a
longer session. Before you begin, check with your doctor about what
type of activity and level of intensity would be most appropriate. A
few possibilities include water aerobics, swimming, tai chi, and
yoga.
Outlook for MS
Most
people with MS live a normal or near-normal lifespan. While the
condition may make it more difficult to get around or complete
certain tasks, it doesn't always lead to severe disability. Thanks to
effective medications, rehab therapies, and assistive devices, many
people with MS remain active, stay in their jobs, and continue to
enjoy their families and favorite activities.